In this study, the surface of magnetic dialdehyde starch nanocomposite has been modified with arginine amino acid (Arg) and employed as an adsorbent for the enrichment of aspartame (ASP) in different real samples. Magnetite dispersive solid-phase microextraction (MDSPME), which had been combined with spectrophotometry, has been used to determine the extracted aspartame. The Plackett–Burman design has been employed to investigate the influence of main parameters including the amount of salt, sample volume, amount of sorbent, dispersive solution volume, desorption, and extraction time, and central composite design has been used to obtain the optimum condition in MDSPME method. Under optimum conditions, 15 ml of sample volume, 1.5 ml of ethanol as dispersive solvent, 10 min of extraction time, 15 min of desorption time, 10 mg of sorbent, and 0 w/v % of salt, the calibration graph has been observed to be linear in a concentration range of 2–15 µg ml⁻¹, while the limit of detection has been 0.064 µg ml⁻¹. The relative standard deviations of 3.64 and 4.12 have been obtained at 8 µg ml⁻¹ level of aspartame for the intra- and inter-day analysis. In addition, the enrichment factor has been about 128. This procedure has been successfully utilized for distinguishing the existing aspartame in two kinds of beverage that had been procured from local markets and drinkable water.

中文翻译：

---

精氨酸官能化磁性纳米复合材料作为吸附剂的分散固相微萃取，用于分离和预浓缩阿斯巴甜，并使用响应面法进行优化

在这项研究中，磁性二醛淀粉纳米复合材料的表面已被精氨酸氨基酸（Arg）修饰，并被用作吸附剂，以富集不同真实样品中的阿斯巴甜（ASP）。磁铁矿分散固相微萃取（MDSPME）与分光光度法相结合，已用于确定提取的阿斯巴甜。Plackett-Burman设计用于研究主要参数的影响，包括盐量，样品量，吸附剂量，分散溶液量，解吸和萃取时间，并且采用中心复合设计来获得最佳条件在MDSPME方法中。在最佳条件下，样品体积为15 ml，乙醇为分散溶剂1.5 ml，萃取时间为10分钟，解吸时间为15分钟，吸附剂为10 mg，0w / v  ％的盐，在2–15 µg ml ^-1的浓度范围内观察到校准曲线是线性的，而检出限为0.064 µg ml ^-1。在日内和日间分析中，阿斯巴甜的浓度为8 µg ml ^-1时，相对标准偏差为3.64和4.12 。此外，富集因子约为128。此程序已成功用于区分从当地市场采购的两种饮料和饮用水中的现有阿斯巴甜。