Introduction Isolated unilateral hypoglossal nerve palsy is an infrequent condition that usually appears in connection to an underlying disease. Rarely, the cause cannot be determined, and there is no symptom remission. Case description We report two cases of male patients who developed persistent idiopathic isolated unilateral hypoglossal nerve palsy. The younger patient complained of involuntary movements of the tongue, while the older patient developed dysarthria. In both cases, the symptoms lasted for several weeks before the initial clinical examination, and after comprehensive clinical, laboratory, and imaging investigations, no underlying cause was detected. Both patients did not show remission of symptoms on the follow-up examinations done after several months. Discussion Idiopathic isolated unilateral hypoglossal nerve palsy is an underreported condition, most likely due to the expected reversible nature of the disease. In the case of persistence of symptoms, extensive medical assessment is needed before postulating a diagnosis of persistent idiopathic isolated unilateral hypoglossal nerve palsy. There are no treatment guidelines for this condition, but oral steroids were reported as a treatment option. Therefore, physicians should use a systematic approach to exclude serious underlying pathology or identify a treatable condition.

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持续性特发性单侧孤立性舌下神经麻痹2例报告

介绍 孤立性单侧舌下神经麻痹是一种罕见的疾病，通常与潜在疾病有关。极少数情况下，无法确定原因，并且没有症状缓解。病例描述 我们报告了两例发生持续性特发性孤立性单侧舌下神经麻痹的男性患者。年轻患者抱怨舌头不自主运动，而年长患者出现构音障碍。在这两种情况下，症状在初次临床检查前持续了数周，经过全面的临床、实验室和影像学检查，没有发现根本原因。在几个月后进行的随访检查中，两名患者均未表现出症状缓解。讨论 特发性孤立性单侧舌下神经麻痹是一种少报情况，很可能是由于该疾病的预期可逆性质。在症状持续存在的情况下，在假定诊断为持续性特发性孤立性单侧舌下神经麻痹之前，需要进行广泛的医学评估。没有针对这种情况的治疗指南，但据报道口服类固醇是一种治疗选择。因此，医生应使用系统方法排除严重的潜在病理或确定可治疗的病症。没有针对这种情况的治疗指南，但据报道口服类固醇是一种治疗选择。因此，医生应使用系统方法排除严重的潜在病理或确定可治疗的病症。没有针对这种情况的治疗指南，但据报道口服类固醇是一种治疗选择。因此，医生应使用系统方法排除严重的潜在病理或确定可治疗的病症。