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Finger-powered fluidic actuation and mixing via MultiJet 3D printing.
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-08-04 , DOI: 10.1039/d0lc00488j Eric Sweet 1 , Rudra Mehta , Yifan Xu , Ryan Jew , Rachel Lin , Liwei Lin
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-08-04 , DOI: 10.1039/d0lc00488j Eric Sweet 1 , Rudra Mehta , Yifan Xu , Ryan Jew , Rachel Lin , Liwei Lin
Affiliation
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Additive manufacturing, or three-dimensional (3D) printing, has garnered significant interest in recent years towards the fabrication of sub-millimeter scale devices for an ever-widening array of chemical, biological and biomedical applications. Conventional 3D printed fluidic systems, however, still necessitate the use of non-portable, high-powered external off-chip sources of fluidic actuation, such as electro-mechanical pumps and complex pressure-driven controllers, thus limiting their scope towards point-of-need applications. This work proposes entirely 3D printed sources of human-powered fluidic actuation which can be directly incorporated into the design of any 3D printable sub-millifluidic or microfluidic system where electrical power-free operation is desired. Multiple modular, single-fluid finger-powered actuator (FPA) designs were fabricated and experimentally characterized. Furthermore, a new 3D fluidic one-way valve concept employing a dynamic bracing mechanism was developed, demonstrating a high diodicity of ∼1117.4 and significant reduction in back-flow from the state-of-the-art. As a result, fabricated FPA prototypes achieved tailorable experimental fluid flow rates from ∼100 to ∼3000 μL min−1 without the use of electricity. Moreover, a portable human-powered two-fluid pulsatile fluidic mixer, capable of generating fully-mixed fluids in 10 seconds, is presented, demonstrating the application of FPAs towards on-chip integration into more complex 3D printed fluidic networks.
中文翻译：
通过MultiJet 3D打印进行手指驱动的流体驱动和混合。
近年来，增材制造或三维（3D）打印已引起人们对于制造亚毫米级设备的广泛兴趣，这些设备用于不断扩大的化学，生物和生物医学应用。但是，传统的3D打印流体系统仍然需要使用非便携式，高功率的外部芯片外流体致动源，例如机电泵和复杂的压力驱动控制器，因此将其范围限制在-需要的应用程序。这项工作提出了人力流体致动的完全3D打印源，可以将其直接合并到需要无电操作的任何3D可打印亚微流体或微流体系统的设计中。多种模块化 制作了单流体手指动力执行器（FPA）设计并进行了实验表征。此外，还开发了一种采用动态支撑机构的新型3D流体单向阀概念，展示了约1117.4的高折光率，并显着减少了现有技术带来的回流。结果，预制的FPA原型实现了从〜100到〜3000μLmin的可定制实验流体流速-1，不用电。此外，提出了一种便携式人力两流体脉动流体混合器，该混合器能够在10秒内产生完全混合的流体，证明了FPA在片上集成到更复杂的3D打印流体网络中的应用。
更新日期：2020-09-15
中文翻译：
通过MultiJet 3D打印进行手指驱动的流体驱动和混合。
近年来，增材制造或三维（3D）打印已引起人们对于制造亚毫米级设备的广泛兴趣，这些设备用于不断扩大的化学，生物和生物医学应用。但是，传统的3D打印流体系统仍然需要使用非便携式，高功率的外部芯片外流体致动源，例如机电泵和复杂的压力驱动控制器，因此将其范围限制在-需要的应用程序。这项工作提出了人力流体致动的完全3D打印源，可以将其直接合并到需要无电操作的任何3D可打印亚微流体或微流体系统的设计中。多种模块化 制作了单流体手指动力执行器（FPA）设计并进行了实验表征。此外，还开发了一种采用动态支撑机构的新型3D流体单向阀概念，展示了约1117.4的高折光率，并显着减少了现有技术带来的回流。结果，预制的FPA原型实现了从〜100到〜3000μLmin的可定制实验流体流速-1，不用电。此外，提出了一种便携式人力两流体脉动流体混合器，该混合器能够在10秒内产生完全混合的流体，证明了FPA在片上集成到更复杂的3D打印流体网络中的应用。
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