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Technical and dosimetric realization of in vivo x-ray microbeam irradiations at the Munich Compact Light Source.
Medical Physics ( IF 3.2 ) Pub Date : 2020-08-05 , DOI: 10.1002/mp.14433
Karin Burger 1, 2 , Theresa Urban 1, 2 , Annique C Dombrowsky 1, 3 , Martin Dierolf 2 , Benedikt Günther 2 , Stefan Bartzsch 1, 3 , Klaus Achterhold 2 , Stephanie E Combs 1, 3 , Thomas E Schmid 1, 3 , Jan J Wilkens 1, 2 , Franz Pfeiffer 2, 4
Affiliation  

X‐ray microbeam radiation therapy is a preclinical concept for tumor treatment promising tissue sparing and enhanced tumor control. With its spatially separated, periodic micrometer‐sized pattern, this method requires a high dose rate and a collimated beam typically available at large synchrotron radiation facilities. To treat small animals with microbeams in a laboratory‐sized environment, we developed a dedicated irradiation system at the Munich Compact Light Source (MuCLS).

中文翻译:

在慕尼黑紧凑型光源上进行体内X射线微束辐照的技术和剂量学实现。

X射线微束放射疗法是用于临床肿瘤治疗的临床前概念,有望保留组织并增强肿瘤控制。由于这种方法具有空间上分开的,周期性的微米大小的图案,因此需要高剂量率和通常在大型同步加速器辐射设施上可获得的准直光束。为了在实验室大小的环境中用微束治疗小型动物,我们在慕尼黑紧凑型光源(MuCLS)上开发了专用的辐照系统。
更新日期:2020-08-05
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