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Tricellulin: The Role of Tricellulin in Epithelial Jamming and Unjamming via Segmentation of Tricellular Junctions (Adv. Sci. 15/2020)
Advanced Science ( IF 15.1 ) Pub Date : 2020-08-05 , DOI: 10.1002/advs.202070085
Sophie Lohmann , Costanza Giampietro , Francesca M. Pramotton , Dunja Al‐Nuaimi , Alessandro Poli , Paolo Maiuri , Dimos Poulikakos , Aldo Ferrari

In confluent epithelial monolayers, tricellular junctions (tTJs) are assembled at vertexes where three cells meet. In article number 2001213, Dimos Poulikakos, Aldo Ferrari, and co‐workers establish the junctional maturity at tricellular contacts as a descriptor of epithelial jamming and unjamming transitions. During tissue maturation, wound healing, or in response to osmolarity changes, epithelial cells collectively adapt their shape and motility along with the modulation of tTJs maturity.
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中文翻译:

甘油三酸酯:甘油三酸酯在三细胞交界处的分段上皮干扰和抗干扰中的作用(Adv。Sci。15/2020)

在汇合的上皮单层中,三细胞接头(tTJ)在三个细胞相遇的顶点处组装。在第2001213号文章中,Dimos Poulikakos,Aldo Ferrari及其同事在三细胞接触处建立了连接成熟度,作为上皮干扰和解除干扰转变的描述。在组织成熟,伤口愈合或对渗透压变化的响应过程中,上皮细胞随着tTJs成熟度的调节共同适应其形状和运动。
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更新日期:2020-08-05
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