Abstract With the present study, we aimed to identify polymorphisms in the genes encoding mitochondrial uncoupling protein 2 (UCP2) and peroxisome proliferator-activated receptor gamma (PPARG), and to evaluate their associations with breeding values for milk production and composition traits in goats. Breeding values were estimated from milk yield and composition data of Saanen and Alpine animals using a single-trait model. The number of animals used for the estimation of breeding values ranged from 1,094 to 1,292, depending on the trait studied. After identification of the polymorphisms, the animals were genotyped for association analysis. Among animals with estimated breeding values, we randomly genotyped 185 for the UCP2.29614171G/A polymorphism located in the promoter region of the UCP2 gene, 176 for the UCP2.29615319G/A polymorphism located in exon 2 of the UCP2 gene, and 194 for the PPARG-A/B polymorphism located in the promoter region of the PPARG gene. For the UCP2 gene, the UCP2.29614171G/A polymorphism showed association (P

中文翻译：

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山羊UCP2和PPARG基因多态性及其与牛奶品质性状的关联

摘要 通过本研究，我们旨在鉴定编码线粒体解偶联蛋白 2 (UCP2) 和过氧化物酶体增殖物激活受体 γ (PPARG) 的基因的多态性，并评估它们与山羊产奶量和成分性状的育种价值的关联。育种值是使用单性状模型根据 Saanen 和 Alpine 动物的产奶量和成分数据估算的。用于估计育种值的动物数量从 1,094 到 1,292 不等，具体取决于所研究的性状。鉴定多态性后，对动物进行基因分型以进行关联分析。在具有估计育种值的动物中，我们对位于 UCP2 基因启动子区域的 UCP2.29614171G/A 多态性进行了 185 次随机基因分型，对 UCP2 进行了 176 次基因分型。29615319G/A 多态性位于 UCP2 基因外显子 2，194 为 PPARG-A/B 多态性位于 PPARG 基因启动子区。对于 UCP2 基因，UCP2.29614171G/A 多态性显示关联（P