A novel chitosan-supported cinchona urea heterogeneous catalyst was developed for asymmetric reaction. The catalytic activity of the chitosan-supported organocatalyst was examined in the asymmetric Michael addition reaction to give chiral adducts in good yields with excellent enantioselectivities (up to 99% ee). The insolubility of the chitosan-supported cinchona urea catalyst facilitated catalyst recovery. The catalyst was easily separated and reused without any loss in catalytic activity.

中文翻译：

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壳聚糖负载的金鸡纳尿素：可持续的有机催化剂，用于不对称迈克尔反应

开发了一种新型的壳聚糖负载金鸡纳尿素非均相催化剂用于不对称反应。在不对称迈克尔加成反应中检查了壳聚糖负载的有机催化剂的催化活性，从而以良好的收率和优异的对映选择性（高达99％ee）得到手性加合物。壳聚糖负载的金鸡纳脲催化剂的不溶性促进了催化剂的回收。催化剂易于分离和再利用，而催化活性没有任何损失。