Electrospinning was used to produce fibrous membranes, in single and multiple layers, from poly(ε-caprolactone), pullulan, and from mixtures of poly(ε-caprolactone) with potato modified starch and β-glucan. It was possible to obtain single-layer membranes from solutions of pullulan in water, poly(ε-caprolactone) in chloroform, and from mixtures of poly(ε-caprolactone)/β-glucan and poly(ε-caprolactone)/potato modified starch in chloroform. Scanning electron microscopy images showed the formation of ultrathin homogeneous fibers from electrospun poly(ε-caprolactone) and pullulan, whereas the fibers obtained from mixtures of poly(ε-caprolactone)/ β -glucan and poly(ε-caprolactone)/potato modified starch had different sizes and morphologies, as well as irregular microstructures, characterized by the presence of beads. Contact angle analyses showed that pullulan membranes were extremely hydrophilic, while poly(ε-caprolactone) membranes were predominantly hydrophobic. Subsequently, poly(ε-caprolactone)-pullulan-poly(ε-caprolactone) multilayer membranes, with intermediate wettability, were prepared by successive electrospinning steps. Infrared spectroscopy and calorimetric analyses showed the presence of both polymers and the absence of changes in their structure and stability due to electrospinning, indicating adequate compatibility between the two polymers. We foresee that the polyester-polysaccharide multilayer membrane might be used as a biodegradable vehicle for active agents with different hydrophobicity, with applications as food packaging and biocompatible scaffold materials.

中文翻译：

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聚己内酯和多糖的超薄单层和多层电纺纤维膜

静电纺丝用于生产单层和多层纤维膜，由聚（ε-己内酯）、支链淀粉以及聚（ε-己内酯）与马铃薯改性淀粉和 β-葡聚糖的混合物制成。可以从支链淀粉的水溶液、聚（ε-己内酯）的氯仿溶液以及聚（ε-己内酯）/β-葡聚糖和聚（ε-己内酯）/马铃薯改性淀粉的混合物中获得单层膜在氯仿中。扫描电子显微镜图像显示由电纺聚（ε-己内酯）和支链淀粉形成的超薄均质纤维，而从聚（ε-己内酯）/β-葡聚糖和聚（ε-己内酯）/马铃薯改性淀粉的混合物中获得的纤维具有不同的尺寸和形态，以及不规则的微观结构，其特征是存在珠子。接触角分析表明，普鲁兰多糖膜具有极强的亲水性，而聚（ε-己内酯）膜主要是疏水性的。随后，通过连续的静电纺丝步骤制备了具有中等润湿性的聚（ε-己内酯）-支链淀粉-聚（ε-己内酯）多层膜。红外光谱和量热分析表明两种聚合物都存在，并且由于静电纺丝，它们的结构和稳定性没有变化，表明两种聚合物之间有足够的相容性。我们预见聚酯-多糖多层膜可用作具有不同疏水性的活性剂的可生物降解载体，可用作食品包装和生物相容性支架材料。而聚（ε-己内酯）膜主要是疏水的。随后，通过连续的静电纺丝步骤制备了具有中等润湿性的聚（ε-己内酯）-支链淀粉-聚（ε-己内酯）多层膜。红外光谱和量热分析表明两种聚合物都存在，并且由于静电纺丝，它们的结构和稳定性没有变化，表明两种聚合物之间有足够的相容性。我们预见聚酯-多糖多层膜可用作具有不同疏水性的活性剂的可生物降解载体，可用作食品包装和生物相容性支架材料。而聚（ε-己内酯）膜主要是疏水的。随后，通过连续的静电纺丝步骤制备了具有中等润湿性的聚（ε-己内酯）-支链淀粉-聚（ε-己内酯）多层膜。红外光谱和量热分析表明两种聚合物都存在，并且由于静电纺丝，它们的结构和稳定性没有变化，表明两种聚合物之间有足够的相容性。我们预见聚酯-多糖多层膜可用作具有不同疏水性的活性剂的可生物降解载体，可用作食品包装和生物相容性支架材料。通过连续的静电纺丝步骤制备。红外光谱和量热分析表明两种聚合物都存在，并且由于静电纺丝，它们的结构和稳定性没有变化，表明两种聚合物之间有足够的相容性。我们预见聚酯-多糖多层膜可用作具有不同疏水性的活性剂的可生物降解载体，可用作食品包装和生物相容性支架材料。通过连续的静电纺丝步骤制备。红外光谱和量热分析表明两种聚合物都存在，并且由于静电纺丝，它们的结构和稳定性没有变化，表明两种聚合物之间有足够的相容性。我们预见聚酯-多糖多层膜可用作具有不同疏水性的活性剂的可生物降解载体，可用作食品包装和生物相容性支架材料。