Background: Numerous studies, ranging from the alleviation of tissue ischemia to the assessment of cancer prognosis, have demonstrated the fundamental biological differences between human umbilical cord blood-derived endothelial progenitor cells (CB-EPCs) and adult peripheral blood-derived endothelial progenitor cells (PB-EPCs). However, the underlying molecular mechanisms that produce these differences are not clear.The purpose of this study was to identify potential hub genes, key protein interactive networks, and correlated signal pathways unique to CB-EPC biology via bioinformatic methods.

中文翻译：

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潜在的枢纽基因和信号通路的鉴定，通过生物信息学促进脐带血来源的内皮祖细胞的独特生物学特性。

背景：从减轻组织局部缺血到评估癌症预后，无数研究表明，人脐带血内皮祖细胞（CB-EPC）与成人外周血内皮祖细胞（ PB-EPC）。然而，产生这些差异的潜在分子机制尚不清楚。本研究的目的是通过生物信息学方法识别CB-EPC生物学独有的潜在中心基因，关键的蛋白质相互作用网络和相关的信号途径。