The transferability of phthalic acid esters (PAEs) and other plasticizers, from model polyvinyl chloride (PVC) sheets to the skin of 11 subjects was assessed by measuring the amount of substance transferred using PVC sheets containing PAEs and alternative plasticizers of different types and contents. For all subjects, the transferred amount, from sheets containing 28 wt% PAE or from mixed sheets containing 14 wt% each of di (2-ethylhexyl) phthalate (DEHP) and other PAE, was greater than that from sheets containing 15 wt% each of PAE or alternative plasticizer only. A comparison of the transferability of five types of PAE showed that transfer tended to occur more readily as the n-octanol-water partition coefficient increased, suggesting that PAE hydrophobicity affected its transferability. The transferability of the alternative plasticizers di(2-ethylhexyl) terephthalate and 1,2-cyclohexane dicarboxylic acid diisononyl ester showed a similar trend; however, the transferred amount tended to be higher from model PVC sheets containing 28 wt% PAE or mixed with DEHP. The transferability of PAEs and alternative plasticizers was higher for certain subjects, suggesting individual differences in the transferability of chemicals to the subject’s skin surface and is the presence of a group of people comparatively more susceptible to such transfer.

邻苯二甲酸酯（PAE）和其他增塑剂从模型聚氯乙烯（PVC）片到11名受试者的皮肤的可转移性通过使用含有PAE和不同类型和含量的替代增塑剂的PVC片测量的物质转移量来评估。对于所有受试者，从含有28 wt％PAE的纸张或含有14 wt％邻苯二甲酸二（2-乙基己基）酯（DEHP）和其他PAE的混合纸张的转印量要大于从各自含有15 wt％的纸张的转印量。仅适用于PAE或替代增塑剂。对五种PAE的可转移性进行比较，结果表明，随着n的增加，转移往往更容易发生。-辛醇-水分配系数增加，表明PAE疏水性影响其转移性。替代增塑剂对苯二甲酸二（2-乙基己基）酯和1,2-环己烷二甲酸二异壬酯的转移性显示出相似的趋势。但是，从含有28wt％PAE或与DEHP混合的模型PVC片材中，转移量倾向于更高。对于某些受试者，PAE和替代增塑剂的传递能力更高，这表明化学物质向受试者皮肤表面的传递能力存在个体差异，并且这是一群人相对更容易受到这种传递的影响。