ABSTRACT Aim: The cluster analysis for the evaluation of the results in Multiplex ISAC test in atopic dermatitis patients. Method: The complete dermatological and allergological examination including the examination of the sensitisation to molecular components with Multiplex ISAC testing was performed. The cluster analysis of molecular components (silhouette value) was processed. Results and conclusion: Altogether 100 atopic dermatitis patients were examined - 48 men, 52 women, the average age 40.9 years. We found 10 clusters with different numbers of molecular components. Fundamental position have the components Phl p 1 (Timothy), Bet v 1 (Birch), Alt a 1 (Alternaria) followed by molecular components of NPC2 family, cystein proteasa, tropomyosin, uteroglobin, lipocalin and PR-10 protein. Our results correspond to the association of molecular components into protein families according to their biochemical structure.

中文翻译：

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根据 ISAC 多重测试对 100 名特应性皮炎患者的分子成分进行聚类分析

摘要 目的：对特应性皮炎患者多重ISAC试验结果进行聚类分析。方法：进行了完整的皮肤病学和过敏学检查，包括使用多重 ISAC 测试检查对分子成分的敏感性。进行了分子成分（轮廓值）的聚类分析。结果与结论：共检查了 100 名特应性皮炎患者——男性 48 名，女性 52 名，平均年龄 40.9 岁。我们发现了 10 个具有不同分子成分数量的簇。基本位置具有成分 Phl p 1 (Timothy)、Bet v 1 (Birch)、Alt a 1 (Alternaria)，其次是 NPC2 家族的分子成分、半胱氨酸蛋白酶、原肌球蛋白、子宫珠蛋白、脂质运载蛋白和 PR-10 蛋白。