An information-based comparison of diffusion attenuation models in normal and inflamed bone marrow.,NMR in Biomedicine

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An information-based comparison of diffusion attenuation models in normal and inflamed bone marrow.
NMR in Biomedicine ( IF 2.7 ) Pub Date : 2020-08-04 , DOI: 10.1002/nbm.4390
Timothy J P Bray ₁ , Alan Bainbridge ₂ , Naomi S Sakai ₁ , Margaret A Hall-Craggs ₁ , Hui Zhang ₃

Affiliation

Diffusion‐weighted imaging has received attention as a method for characterizing inflammatory exudates in bone marrow in immune‐mediated inflammatory diseases and reveals an increase in diffusivity in regions of bone marrow oedema. Various models of diffusion attenuation have been investigated but the model providing the best description of tissue pathophysiology in regions of marrow oedema is unknown. Determining the most appropriate model is an important step towards protocol optimization and the development of a robust and clinically useful method.

中文翻译：

正常和发炎骨髓中扩散衰减模型的基于信息的比较。

弥散加权成像作为一种在免疫介导的炎症性疾病中表征骨髓中炎性渗出物的方法受到了关注，并揭示了骨髓水肿区域的弥散性增加。已经研究了各种扩散衰减模型，但提供骨髓水肿区域组织病理生理学最佳描述的模型尚不清楚。确定最合适的模型是实现方案优化和开发稳健且临床有用的方法的重要一步。

更新日期：2020-10-05

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