Severe reaction to radiotherapy provoked by hypomorphic germline mutations in ATM (ataxia-telangiectasia mutated gene).,Molecular Genetics & Genomic Medicine

当前位置： X-MOL 学术 › Mol. Genet. Genomic Med. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Severe reaction to radiotherapy provoked by hypomorphic germline mutations in ATM (ataxia-telangiectasia mutated gene).
Molecular Genetics & Genomic Medicine ( IF 1.5 ) Pub Date : 2020-08-03 , DOI: 10.1002/mgg3.1409
Reza Asadollahi ₁ , Christian Britschgi ₂ , Pascal Joset ₁ , Beatrice Oneda ₁ , Detlev Schindler ₃ , Urs R Meier ₄ , Anita Rauch _{1,

5}

Affiliation

A minority of breast cancer (BC) patients suffer from severe reaction to adjuvant radiotherapy (RT). Although deficient DNA double‐strand break repair is considered the main basis for the reactions, pretreatment identification of high‐risk patients has been challenging.

中文翻译：