Clostridioides difficile infections (CDIs) are infamous healthcare-associated infections for causing watery diarrhea to long-term hospitalized patients with a high mortality rate. Epidemiological reports from western countries showed up-trending pattern in the number of CDIs cases. It is becoming immensely challenging for routine diagnostic protocols to detect CDIs accurately with short turnaround time. In Saudi Arabia, there is a paucity of data about CDIs’ prevalence, recurrence rate, methods of screening and mortality rate. Nevertheless, a growing number of cases with similar virulence strains and comparable antibiotic resistance pattern to the western countries counterparts reported data were also detected. This review aims to present the status of CDIs’ diagnosis and incidence rate in Saudi Arabia based on current literature.

艰难梭菌感染（CDI）是臭名昭著的与医疗保健相关的感染，可导致长期住院的高死亡率患者出现水样腹泻。西方国家的流行病学报告显示CDI病例数呈上升趋势。常规诊断协议在短周转时间内准确检测CDI变得越来越具有挑战性。在沙特阿拉伯，关于CDI的患病率，复发率，筛查方法和死亡率的数据很少。然而，也发现了越来越多的具有类似毒力菌株和与西方国家相应报告的数据相似的抗生素耐药性模式的病例。本文旨在根据现有文献介绍沙特阿拉伯CDI的诊断和发生率。