Abstract Stable isotopes of light elements, such as 13C, 18O and 15N are used as markers in medicine, pharmacy, biology and other sciences. The demand for isotopes is continuously rising. It will lead to the extension of existing production capacities in the next years and could trigger the development of corresponding processes and systems. The most important issue concerns the optimization of the isotopes production costs. It would be a key factor for the establishment and commoditization of isotope-based methods for everyday life and could improve the quality of health care worldwide. The most economical approach to industrial scale production of stable isotopes is the cryogenic distillation. This method uses the difference in substances’ vapor pressures for separation purposes. But only limited data on the vapor pressure curves of isotopes is currently available, which affects the development of new processes. A new method to predict vapor pressures for stable isotopes is described in the present work. The method is based on a combination of the theory of corresponding states with limited experimental data on the vapor pressure ratios of isotopes available in the literature. This method allows to generate parameters like the critical temperature and pressure for isotopes and isotope-containing gases. In the present work this method is applied to carbon monoxide based on the carbon isotopes.

中文翻译：

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预测同位素和含同位素气体的蒸气压的方法

摘要 13C、18O、15N等轻元素的稳定同位素在医学、药学、生物学等科学中被用作标记物。对同位素的需求不断上升。这将导致未来几年现有生产能力的扩展，并可能引发相应流程和系统的开发。最重要的问题涉及同位素生产成本的优化。这将是在日常生活中建立基于同位素的方法并将其商品化的关键因素，并可以提高全球卫生保健的质量。工业规模生产稳定同位素最经济的方法是低温蒸馏。该方法利用物质蒸气压的差异进行分离。但目前只有有限的同位素蒸气压曲线数据可用，这影响了新工艺的开发。目前的工作描述了一种预测稳定同位素蒸气压的新方法。该方法基于相应状态理论与文献中可用的同位素蒸气压比的有限实验数据相结合。该方法允许生成诸如同位素和含同位素气体的临界温度和压力之类的参数。在目前的工作中，这种方法适用于基于碳同位素的一氧化碳。该方法基于相应状态理论与文献中可用的同位素蒸气压比的有限实验数据相结合。该方法允许生成诸如同位素和含同位素气体的临界温度和压力之类的参数。在目前的工作中，这种方法适用于基于碳同位素的一氧化碳。该方法基于相应状态理论与文献中可用的同位素蒸气压比的有限实验数据相结合。该方法允许生成诸如同位素和含同位素气体的临界温度和压力之类的参数。在目前的工作中，这种方法适用于基于碳同位素的一氧化碳。