Psychological stress has long been known to reduce adaptability to inflammatory challenges, although the precise mechanism has remained elusive. In a recent issue of Cell, Qing et al. (2020) demonstrate that psychological stress induces secretion of IL-6 from brown adipose tissue, which promotes hepatic gluconeogenesis, and reduces host fitness to inflammatory insults.

中文翻译：

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压力和IL-6之间的联系正在升温。

人们早就知道心理压力会降低对炎症挑战的适应性，尽管确切的机制仍然难以捉摸。在《细胞》杂志的最新一期中，Qing等人。（2020）证明心理压力诱导棕色脂肪组织分泌IL-6，促进肝糖异生，并降低宿主对炎症的适应性。