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Scaling up dissection of functional RNA elements.
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2020-08-03 , DOI: 10.1038/s41594-020-0482-9
Marc Bühler 1, 2 , Alex Charles Tuck 3
Affiliation  

Translation and mRNA decay are tightly connected processes governing protein production, and their regulation involves an elaborate network of protein factors and sequence elements. A massively parallel RNA-based reporter system now reveals regulatory pathways triggered by 5′ UTR elements and allows dissection of the interplay between translation and mRNA decay.

中文翻译:

扩大功能性RNA元件的解剖。

翻译和mRNA衰减是控制蛋白质生产的紧密联系过程,其调控涉及蛋白质因子和序列元件的精细网络。大规模平行的基于RNA的报告系统现在揭示了5'UTR元件触发的调控途径,并允许解剖翻译和mRNA衰减之间的相互作用。
更新日期:2020-08-03
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