Abstract

The genus Saussurea DC is well known for its rich chemical composition and wide range of biological activities. Although content and biological effects of major chemical components are thoroughly studied, the composition and concentrations of minor constituents, such as essential oils, still remains unclear. In total, 62 different chemical compounds have been identified in the essential oils from S. controversa, S. latifolia, S. parviflora and S. salicifolia using a gas chromatography–mass spectrometry method. The essential oils include 1–5% of linalool, 2–7% of eudesmol and oxygen-containing sesquiterpenoids: 7–25% of caryophyllene oxide, 4–5% of spathulenol, 4–6% of humulene-6.7-oxide. The presence of sesquiterpenoids can be considered as a chemotaxonomic feature of the studied species of Saussurea DC. The essential oils can be candidates for new anti-inflammatory, analgesic and anti-tumor drugs due to relatively high concentration of caryophyllene oxide.

摘要

雪莲属DC 以其丰富的化学成分和广泛的生物活性而闻名。尽管对主要化学成分的含量和生物效应进行了深入研究，但精油等次要成分的组成和浓度仍不清楚。总共在S. controversa、S. latifolia、S. parviflora和S. salicifolia的精油中鉴定出 62 种不同的化合物使用气相色谱-质谱法。精油包括 1-5% 的芳樟醇、2-7% 的 eudesmol 和含氧倍半萜类化合物：7-25% 的石竹烯、4-5% 的绿萝、4-6% 的 Humulene-6.7-oxide。倍半萜类化合物的存在可以被认为是所研究的雪莲属DC 物种的化学分类学特征。由于石竹烯氧化物的浓度相对较高，精油可以成为新的抗炎、镇痛和抗肿瘤药物的候选者。