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Anti-stress effects of rosemary (Rosmarinus officinalis L.) leaf extract on intestinal goblet cells and immobility of forced-swimming test in BALB/c mice.
Bioscience, Biotechnology, and Biochemistry ( IF 1.4 ) Pub Date : 2020-08-02 , DOI: 10.1080/09168451.2020.1800445
Tomoko Kayashima 1 , Koji Nagao 2 , Mituki Umino 3 , Hiroko Kaikiri 4 , Sachi Shibata 5 , Kiminori Matsubara 3, 6
Affiliation  

ABSTRACT

We investigated the anti-stress effect of rosemary (Rosmarinus officinalis L.) leaf extract (RLE) on restraint-stressed mice and found that RLE alleviated decreases in the number of intestinal goblet cells and amount of hepatic triglycerides. It also decreased the immobility time in the forced-swimming test and activation of microglia in the brain, suggesting that RLE has beneficial effects on stress-induced dysfunctions.



中文翻译:

迷迭香(Rosmarinus officinalis L.)叶提取物对小肠杯状细胞的抗应激作用和BALB / c小鼠强制游泳试验的固定性。

摘要

我们调查了迷迭香(迷迭香)叶提取物(RLE)对束缚应激小鼠的抗应激作用,发现RLE减轻了肠道杯状细胞数量和肝甘油三酯含量的减少。它也减少了强迫游泳测试中的不动时间和大脑中小胶质细胞的激活,这表明RLE对压力引起的功能障碍具有有益的作用。

更新日期:2020-08-02
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