The modification of quinoxalin-2(1H)-ones via direct C-H bond functionalization has recently received widespread attention, due to the quinoxalin-2(1H)-one derivatives’ various biological activities and pharmaceutical properties. This mini review concentrates on the accomplishments of arylation, trifluoromethylation, alkylation and alkoxylation of quinoxalin-2(1H)-ones with hypervalent iodine(III) reagents as reaction partners or oxidants. The reaction conditions and mechanisms are compared and discussed in detail.

中文翻译：

---

喹喔啉-2（1H）-与高价碘（III）试剂的C3-H键功能化。

由于喹喔啉-2（1H）-one衍生物的各种生物学活性和药物特性，通过直接CH键官能化对喹喔啉-2（1H）-one的修饰近来受到广泛关注。这篇简短的综述集中在用高价碘（III）试剂作为反应伴侣或氧化剂的喹喔啉-2（1H）-酮的芳基化，三氟甲基化，烷基化和烷氧基化方面。比较并详细讨论了反应条件和机理。