Stress has been shown to adversely affect pregnancy outcomes. Neighborhood crime rates may serve as one publicly available social determinant of health for pregnancy studies that use registry or electronic health record datasets in which individual-level stress data are not available. We sought to determine whether neighborhood violent crime incidents were associated with measured perceived stress in a largely minority, urban pregnancy cohort. We performed a secondary analysis of the 1309 Philadelphia residents participating in the Motherhood and Microbiome cohort (n = 2000) with both neighborhood violent crime and Cohen’s Perceived Stress Scale (PSS-14) data. Generalized linear mixed models accounting for confounding variables and geographic clustering demonstrated that, regardless of race, women with the highest quartile of neighborhood violent crime had significantly elevated odds of high stress compared to women with lower crime. We also found that Black women were more likely to have both the highest quartile of neighborhood violent crime and high stress than non-Black women. Overall, this study demonstrates that neighborhood violent crime is associated with perceived stress in pregnancy. Given disparate exposure to crime and prenatal stress by race, future work is warranted to determine whether urban neighborhood violence and/or stress reduction strategies would improve birth outcome racial disparities.

中文翻译：

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邻里暴力犯罪和怀孕期间的压力感知。

压力已被证明会对妊娠结局产生不利影响。社区犯罪率可以作为怀孕研究中公开的健康健康决定因素之一，这些研究使用登记或电子健康记录数据集，其中无法获得个人层面的压力数据。我们试图确定社区暴力犯罪事件是否与主要少数城市怀孕人群的感知压力有关。我们使用社区暴力犯罪和科恩感知压力量表 (PSS-14) 数据对参与母性和微生物组队列 ( n = 2000) 的 1309 名费城居民进行了二次分析。考虑混杂变量和地理聚类的广义线性混合模型表明，无论种族如何，与犯罪率较低的女性相比，邻里暴力犯罪最高四分位数的女性承受高压力的几率显着升高。我们还发现，与非黑人女性相比，黑人女性更有可能遭受邻里暴力犯罪率最高的四分之一，并且压力更大。总的来说，这项研究表明，邻里暴力犯罪与怀孕期间的压力有关。鉴于不同种族的犯罪和产前压力存在差异，未来的工作有必要确定城市邻里暴力和/或减压策略是否会改善出生结果的种族差异。