Aquaculture development is limited by bacteria associated with several diseases; antibiotics are used for the treatment of these affections, but bacteria have developed resistance to these drugs. It is important to develop effective treatments that allow the production of antibiotic-free food. The aim of the present study is to evaluate the in vitro antibacterial effects of Salix babylonica hydro-alcoholic extract (SbHE) against Aeromonas hydrophila, Listonella anguillarum, Edwarsiella tarda, and Streptococcus iniae, bacteria that affect Oncorhynchus mykiss and Oreochromis spp. production. SbHE was obtained through the maceration technique. Reference strains were used and their sensitivity to antibiotics was determined. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of SbHE were determined. Results showed that three of four evaluated bacteria were multidrug resistant, except S. iniae. SbHE showed antibacterial activity against all bacteria. Results indicate an MIC of 1.56 to 25 mg/mL and an MBC of 3.12 to 100 mg/mL. The greatest inhibitory activity occurred against L. anguillarum obtaining a MIC of 1.56 mg/mL and an MBC of 3.12 mg/mL. Results indicate that SbHE has bactericidal activity against A. hydrophila, L.anguilalurm, and S. iniae as well as bacteriostatic activity against E. tarda and could be an alternative treatment against these bacteria.

中文翻译：

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柳柳提取物对影响Oncorhynchus mykiss和Oreochromis spp的细菌的体外抗菌潜力。

水产养殖的发展受到与几种疾病有关的细菌的限制。抗生素用于治疗这些情感，但是细菌对这些药物产生了抗药性。开发有效的治疗方法以生产不含抗生素的食物非常重要。本研究的目的是评估中的体外抗菌效果垂柳水-醇提取物（SBHE）抗嗜水，鳗利斯顿氏菌，Edwarsiella氏菌，和海豚链球菌，影响细菌虹鳟和尼罗spp。生产。通过浸软技术获得SbHE。使用参考菌株并确定其对抗生素的敏感性。确定了SbHE的最小抑菌浓度（MIC）和最小杀菌浓度（MBC）。结果表明，除猪链球菌外，四个评估细菌中的三个具有多重耐药性。SbHE对所有细菌均表现出抗菌活性。结果表明，MIC为1.56至25 mg / mL，MBC为3.12至100 mg / mL。对安圭拉菌的抑制作用最大，MIC为1.56 mg / mL，MBC为3.12 mg / mL。结果表明，SBHE具有抗杀菌活性嗜水气，L. anguilalurm，和海豚链球菌以及针对焦油大肠埃希菌的抑菌活性，可能是针对这些细菌的另一种治疗方法。