The objectives of the study were to evaluate haemodynamic changes and their relationships among ipsilateral (IPS) and contralateral (CONT) uterine arteries (UA) during different stages of pregnancy in Bos indicus cows. Multiparous pregnant cows (n = 40) having a gestation length 30.47 ± 0.54 (mean ± SD) days were randomly enrolled and subjected to Doppler ultrasonography sequentially at 1st, 2nd, 4th, 6th and 8th months of gestation. Blood flow indices including diameter of UA (mm), blood flow volume (BFVo, ml/min), blood flow velocity (BFVe, cm/s), time‐averaged maximum velocity (TAMV, cm/s), pulsatility index (PI) and resistance index (RI) were recorded. Data were analysed with mixed models using the PROC MIXED procedures, and Pearson correlation coefficients were calculated using the PROC CORR statement in SAS. The final statistical models included the fixed effects of side of UA, gestation month and the interaction between side of UA and gestation month. Results revealed that the mean diameter of the UA (12.13 ± 0.22 vs. 10.09 ± 0.22), BFVo (1236.33 ± 0.55 vs. 770.41 ± 0.55), BFVe (17.18 ± 0.42 vs. 15.58 ± 0.42) and TAMV (17.11 ± 0.44 vs. 15.77 ± 0.44) was higher (p < .05) in IPS as compared to CONT side of the UA in cows. However, PI and RI did not differ between IPS and CON arteries of uterus in cows. A very high and positive correlation (r = .89; p < .05) existed between the diameter of UA and BFVo starting from 1st to 8th months of gestation in IPS as well as CONT sides of UA. Moreover, TAMV was highly and positively correlated (r = .91; p < .05) with BFVe throughout the gestation. In conclusion, these haemodynamic changes in the UA could be used as a valuable validity tool to differentiate the compromised pregnancy in Bos indicus cows.

中文翻译：

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使用多普勒超声评估 Bos indicus 母牛妊娠不同阶段子宫动脉血流动力学变化。

该研究的目的是评估Bos indicus母牛在妊娠不同阶段的血流动力学变化及其同侧 (IPS) 和对侧 (CONT) 子宫动脉 (UA) 之间的关系。经产妊娠母牛 ( n =  40) 的妊娠长度为 30.47 ± 0.54（平均值 ±  SD) 天被随机登记并在妊娠第 1、2、4、6 和 8 个月依次接受多普勒超声检查。血流指标包括 UA 直径 (mm)、血流量 (BFVo, ml/min)、血流速度 (BFVe, cm/s)、时间平均最大流速 (TAMV, cm/s)、搏动指数 (PI) ) 和阻力指数 (RI)。使用 PROC MIXED 程序使用混合模型分析数据，并使用 SAS 中的 PROC CORR 语句计算 Pearson 相关系数。最终的统计模型包括 UA 侧、孕月的固定效应以及 UA 侧和妊娠月之间的交互作用。结果显示 UA 的平均直径 (12.13 ± 0.22 vs. 10.09 ± 0.22)、BFVo (1236.33 ± 0.55 vs. 770.41 ± 0.55)、BFVe (17.18 ± 0.42 vs. 15.40 vs. 15.40) ±15.40 .与奶牛 UA 的 CONT 侧相比，IPS 中的p <  .05)。然而，PI 和 RI 在奶牛子宫的 IPS 和 CON 动脉之间没有差异。从妊娠第 1 个月到第 8 个月，在 IPS 以及 UA 的 CONT 侧，UA 的直径和 BFVo 之间存在非常高的正相关（r  = .89；p <  .05）。此外，TAMV 在整个妊娠期间与 BFVe呈高度正相关 ( r  = .91；p <  .05)。总之，UA 中的这些血流动力学变化可用作区分Bos indicus奶牛妊娠受损的有价值的有效性工具。