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The zebrafish histamine H3 receptor modulates aggression, neural activity and forebrain functional connectivity.
Acta Physiologica ( IF 5.6 ) Pub Date : 2020-08-02 , DOI: 10.1111/apha.13543
Florian Reichmann 1, 2 , Neal Rimmer 1 , Ceinwen A Tilley 1 , Elisa Dalla Vecchia 1 , Joseph Pinion 3 , Amir Al Oustah 1 , Hector Carreño Gutiérrez 1 , Andrew M J Young 1 , Jonathan R McDearmid 1 , Matthew J Winter 3 , William H J Norton 1, 4
Affiliation  

Aggression is a behavioural trait characterized by the intention to harm others for offensive or defensive purposes. Neurotransmitters such as serotonin and dopamine are important mediators of aggression. However, the physiological role of the histaminergic system during this behaviour is currently unclear. Here, we aimed to better understand histaminergic signalling during aggression by characterizing the involvement of the histamine H3 receptor (Hrh3).

中文翻译:


斑马鱼组胺 H3 受体调节攻击性、神经活动和前脑功能连接。



攻击性是一种行为特征,其特征是出于进攻或防御目的而意图伤害他人。血清素和多巴胺等神经递质是攻击性的重要介质。然而,组胺能系统在这种行为中的生理作用目前尚不清楚。在这里,我们的目的是通过表征组胺 H3 受体 (Hrh3) 的参与来更好地了解攻击过程中的组胺能信号传导。
更新日期:2020-08-02
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