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Effect of Methotrexate is Changed under Conditions of High Temperature of Ontogenesis as Exemplified by Drosophila melanogaster
Bulletin of Experimental Biology and Medicine ( IF 0.9 ) Pub Date : 2020-07-01 , DOI: 10.1007/s10517-020-04889-4
O N Antosyuk 1 , A D Suvorova 1
Affiliation  

Changes in the effect of methotrexate (400 μg/kg nutrient medium) combined with high temperature (28°C) of ontogenesis were studied on two hybrid lines of Drosophila melanogaster heterozygous by the vestigial gene that underwent long-term target selection for cutting injury of the wing. Changes in the wing shape, mortality rate, and morphology of polytene chromosomes were studied.

中文翻译:

以黑腹果蝇为例,在个体发生的高温条件下甲氨蝶呤的作用发生变化

研究了甲氨蝶呤(400 μg/kg 营养培养基)结合高温(28°C)个体发育对黑腹果蝇(Drosophila melanogaster)两个杂合系的影响变化。机翼。研究了翅膀形状、死亡率和多线染色体形态的变化。
更新日期:2020-07-01
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