The macroscopic and histological methods were employed to examine the autopsy specimens of salivary lingual glands obtained from 299 patients of both sexes and various age ranging from newborn to longevity. The age-associated alterations of minor lingual and pharyngeal glands were revealed, and the topographical relations between the glands and lymphoid cells were described. The characteristic sparsity of the glands in infancy is caused by nutritional uniformity at this period, when diminished production of secretory IgA results in frequent inflammatory processes in oral and pharyngeal cavities. With age, the glandular orifices widen, and their number increases thereby augmenting local immunity in the oral cavity and in oral aspect of the pharynx. Starting from elderly and senile age, the involutive alterations were observed, which were accompanied by diminished production of secretory immunoglobulin A and related degradation of local and humoral immunity.

中文翻译：

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舌腺和咽腺在口腔局部免疫中的年龄相关作用

采用宏观和组织学方法检查了从新生儿到长寿的不同年龄的299名男女患者的唾液舌腺尸体解剖标本。揭示了小舌腺和咽腺的年龄相关改变，并描述了腺体和淋巴细胞之间的地形关系。婴儿时期腺体的特征性稀疏是由这一时期的营养均匀性引起的，此时分泌性 IgA 的产生减少导致口腔和咽腔中频繁的炎症过程。随着年龄的增长，腺孔变宽，它们的数量增加，从而增强口腔和咽部口腔方面的局部免疫力。从老年人和老年开始，观察到内卷的变化，