Abstract: Background Valerian root is an herbal supplement used for its anxiolytic and sedative properties. Its extract is thought to serve as an allosteric modulator of gamma-aminobutyric acid A, which can cause delirium due to its influence on the nervous system’s inhibitory tone and its effect on the sleep-wake cycle. Objective This report presents a patient who developed delirium secondary to withdrawal from valerian root. Conclusion This report emphasizes the importance of screening for use and abstinence of herbal supplements when delirium develops, as herbal supplement withdrawal can be an uncommon and overlooked etiology of delirium.

中文翻译：

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缬草根停药后谵妄：病例报告

摘要：背景 缬草根是一种草药补充剂，具有抗焦虑和镇静作用。它的提取物被认为是 γ-氨基丁酸 A 的变构调节剂，由于其对神经系统的抑制性和睡眠-觉醒周期的影响，可导致谵妄。目的 本报告介绍了一名因拔除缬草根而继发谵妄的患者。结论 该报告强调了在谵妄发生时筛查使用和停止使用草药补充剂的重要性，因为停止使用草药补充剂可能是一种罕见且被忽视的谵妄病因。