Tetracapsuloides bryosalmonae (Myxozoa: Malacosporea) is the causative agent of proliferative kidney disease (PKD), which affects both wild and farmed salmonid fish. The objective of this study was to outline differences in susceptibility to PKD in different salmonid species, hybrids and breeding lineages. Susceptibility to T. bryosalmonae infection was established based on cumulative mortality, pathological findings and detection of T. bryosalmonae in the kidney using immunohistochemistry and molecular methods. Determination of pure and hybrid individuals of different species in the genus Salvelinus, and dissimilarity of rainbow trout lineages, was performed using traditional polymerase chain reaction (PCR) and microsatellite analyses. Rainbow trout displayed higher disease severity compared with brook trout and Alsatian charr. Moreover, the results indicated differences in infection susceptibility, not only among different salmonid species but also among different lineages of charr and rainbow trout. Our study indicated that some salmonid species and even different lineages of the same species are more suitable for farming under PKD pressure.

中文翻译：

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野外研究表明鲑鱼种及其谱系对增生性肾脏疾病的敏感性差异。

四角囊藻苔藓小球藻（Myxozoa：马拉科孢子虫）是增生性肾脏病（PKD）的病原体，它会影响野生和养殖鲑鱼。这项研究的目的是概述不同鲑科物种，杂种和育种谱系对PKD的敏感性差异。敏感性T. bryosalmonae基于累积死亡率，病理结果和检测，建立感染T. bryosalmonae使用免疫组织化学和分子生物学方法的肾脏。Salvelinus属中不同物种的纯种和杂种个体的测定和虹鳟谱系的异质性，是使用传统的聚合酶链反应（PCR）和微卫星分析进行的。与河鳟和阿尔萨斯鲑鱼相比，虹鳟显示出更高的疾病严重性。此外，结果表明，不仅在不同种类的鲑鱼之间，而且在不同种类的鲑鱼和虹鳟鱼中，感染的敏感性也不同。我们的研究表明，某些鲑科物种甚至同一物种的不同谱系更适合在PKD压力下养殖。