The highly efficient catalytic abilities of some mixed oxides are due to cooperative interactions between acid and base functional groups present in their active sites. New La₂O₂CO₃-TiO₂ mixed oxide catalysts with different La/Ti molar ratios successfully synthesized through a facile solvothermal method were investigated for the Knoevenagel condensation reaction of various carbonyl compounds derivatives with malononitrile. The analytical determinations, including XRD, Raman, HRTEM, N₂ adsorption/desorption and TPD of CO₂ and NH₃, witnessed the structural characteristics of the as-prepared La₂O₂CO₃-TiO₂ mixed oxide catalysts. La₂O₂CO₃-TiO₂ mixed oxide catalyst having molar ratio La/La + Ti = 0.09 composition (La₂O₂CO₃(0.09)-TiO₂) exhibited highest conversion of benzaldehyde for Knoevenagel reaction of benzaldehyde with malononitrile. More importantly, this catalyst could be successfully applicable to the Knoevenagel condensation of various carbonyl compounds derivatives with high yields above 85%. This acid-base bifunctional synergetic effect between La₂O₂CO₃ and TiO₂ contributes to improve the catalytic property of the catalyst.

一些混合氧化物的高效催化能力是由于其活性位点中存在的酸与碱官能团之间的协同相互作用。通过简便的溶剂热方法成功地合成了具有不同La / Ti摩尔比的新型La ₂ O ₂ CO ₃ -TiO ₂混合氧化物催化剂，用于各种羰基化合物衍生物与丙二腈的Knoevenagel缩合反应。X 2，拉曼，HRTEM，CO ₂和NH _3的N ₂吸附/解吸和TPD的分析测定结果证明了所制备的La ₂ O ₂ CO的结构特征。_3- TiO ₂混合氧化物催化剂。具有摩尔比La / La + Ti ＝ 0.09组成的La ₂ O ₂ CO ₃ -TiO ₂混合氧化物催化剂（La ₂ O ₂ CO ₃（0.09）-TiO ₂）对于苯甲醛与丙二腈的Knoevenagel反应显示出最高的苯甲醛转化率。更重要的是，该催化剂可以成功地用于各种羰基化合物衍生物的Knoevenagel缩合反应，收率高于85％。La ₂ O ₂ CO ₃与TiO ₂之间的这种酸碱双功能协同作用 有助于改善催化剂的催化性能。