Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health. Human alphaviral disease presents with either arthritogenic or encephalitic manifestations and is associated with significant morbidity and/or mortality. Unfortunately, there are presently no vaccines or antiviral measures approved for human use. The present review examines the ecology, epidemiology, disease, past outbreaks, and potential to cause contemporary outbreaks for several alphavirus pathogens.

中文翻译：

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流行性甲病毒：生态学、出现和爆发。


在过去的一个世纪中，节肢动物传播的人畜共患病原体的出现/重新出现已成为日益严重的公共卫生问题。特别是，甲病毒属的病原体对动物和人类健康构成重大风险。人类甲病毒疾病表现为关节炎或脑炎表现，并与显着的发病率和/或死亡率相关。不幸的是，目前还没有批准用于人类使用的疫苗或抗病毒措施。本综述研究了几种甲病毒病原体的生态学、流行病学、疾病、过去的爆发以及引起当前爆发的潜力。