Bovine mastitis is the predominant cause for antimicrobial use on dairy farms and is a major source of economic losses in the dairy industry. In this study, the antimicrobial susceptibility profiles of common mastitis-causing pathogens, Staphylococcus aureus (n = 62), Streptococcus agalactiae (n = 46), and Escherichia coli (n = 129), were determined for dairy cattle with mastitis across 142 Ukrainian farms. The results showed that there were more gentamicin resistant S. aureus isolates (16.95%) identified in this study than previously reported for Ukrainian dairy cattle. Moreover, low levels of amoxicillin susceptibly (13.51%) were observed for St. agalactiae, which contrasted a previous study showing susceptibility levels of >50%. St. agalactiae resistance to tetracycline was observed in 80% of the isolates. Cephalosporin use was most ineffective against E. coli, with 43.27–56% of the isolates exhibiting this resistant trait. Overall, this study performed a preliminary analysis of antimicrobial resistance on mastitis isolates from Ukrainian farms. However, given the limited numbers of the isolates tested in this study and that the publications on antimicrobial resistance in animal husbandry of Ukraine are very few, more extensive investigations are needed to comprehensively examine susceptibility patterns of mastitis-causing pathogens in dairy cattle in Ukraine.

中文翻译：

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从乌克兰乳业奶牛分离的金黄色葡萄球菌，无乳链球菌和大肠杆菌的抗菌药敏感性。

牛乳腺炎是奶牛场使用抗菌药物的主要原因，也是奶业经济损失的主要来源。在这项研究中，确定了导致乳腺炎的奶牛在142个乌克兰人中常见的引起乳腺炎的病原体，金黄色葡萄球菌（n = 62），无乳链球菌（n = 46） 和大肠埃希菌（n = 129）的敏感性。 农场。结果表明，对庆大霉素耐药的金黄色葡萄球菌更多在这项研究中鉴定的分离株（16.95％）比以前报道的乌克兰奶牛的分离株高。此外，无乳链球菌对阿莫西林的敏感性很低（13.51％）， 这与先前的研究显示敏感性水平> 50％形成对比。在80％的分离物中观察到圣无乳杆菌对四环素的抗性。头孢菌素的使用对大肠杆菌最无效， 有43.27–56％的分离株表现出这种抗性。总体而言，这项研究对来自乌克兰农场的乳腺炎分离株进行了耐药性初步分析。但是，鉴于在这项研究中测试的分离物数量有限，而且乌克兰畜牧业中有关抗菌素耐药性的出版物很少，因此需要进行更广泛的研究，以全面检查 乌克兰奶牛中引起乳腺炎的病原体的易感性。