Evaluating a targeted multiple reaction monitoring approach to global untargeted lipidomic analyses of human plasma.,Rapid Communications in Mass Spectrometry

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Evaluating a targeted multiple reaction monitoring approach to global untargeted lipidomic analyses of human plasma.
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-08-01 , DOI: 10.1002/rcm.8911
Mostafa J Khan ₁ , Simona G Codreanu _{1,

2,

3} , Sandeep Goyal ₁ , Phillip A Wages ₁ , Santosh K K Gorti ₄ , Mackenzie J Pearson ₄ , Isabel Uribe ₅ , Stacy D Sherrod _{1,

2,

3} , John A McLean _{1,

2,

3} , Ned A Porter _{1,

3} , Renã A S Robinson _{1,

3,

6}

Affiliation

The Lipidyzer platform was recently updated on a SCIEX QTRAP 6500+ mass spectrometer and offers a targeted lipidomics assay including 1150 different lipids. We evaluated this targeted approach using human plasma samples and compared the results against a global untargeted lipidomics method using a high‐resolution Q Exactive HF Orbitrap mass spectrometer.

中文翻译：

评估对人血浆进行全局非靶向脂质组学分析的靶向多反应监测方法。

Lipidyzer 平台最近在 SCIEX QTRAP 6500+ 质谱仪上进行了更新，提供了包括 1150 种不同脂质的靶向脂质组学测定。我们使用人类血浆样本评估了这种靶向方法，并将结果与使用高分辨率 Q Exactive HF Orbitrap 质谱仪的全局非靶向脂质组学方法进行了比较。

更新日期：2020-09-12

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