A three‐level five‐factor central composite design was used for microwave‐assisted extraction of bioactive compounds from eggplant peel. The extraction yields, total phenolic content (TPC), total flavonoid content (TFC), total anthocyanin content (TAC), and DPPH radical scavenging activity, reported as IC₅₀, were optimized by changing the microwave power, extraction time, liquid–solid ratio, ethanol concentration, and pH of solvent. The extraction yield, TAC, TPC, and TFC significantly increased (p < .01) parallel to the increase in microwave power and the use of lower ethanol concentrations and lower liquid–solid ratios. The maximum predicted extraction yield (3.27%), TPC (1,049.84 µg GAE/ml), TFC (130.40 µg QE/ml), and TAC (6.99 mg/L) and the minimum predicted IC50 (0.52 ml/mg) were simultaneously obtained when power, extraction time, liquid–solid ratio, ethanol concentration, and pH of solvent were 269.82 W, 7.98 min, 5.01 ml/g, 73.49%, and 3.06%, respectively. Overall, bioactive compounds could be effectively extracted from eggplant peels via optimized microwave conditions.

中文翻译：

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微波辅助从茄子皮副产物中提取生物活性化合物的评估和优化

采用三级五因素中心复合设计，从微波辅助提取茄子皮中的生物活性化合物。通过改变微波功率，提取时间，液固，优化了提取率，总酚含量（TPC），总黄酮含量（TFC），总花色苷含量（TAC）和DPPH自由基清除活性（报告为IC _50）。比例，乙醇浓度和溶剂的pH。提取率，TAC，TPC和TFC显着增加（p <.01）与微波功率的增加以及较低乙醇浓度和较低液固比的使用平行。同时获得最大预计提取率（3.27％），TPC（1,049.84 µg GAE / ml），TFC（130.40 µg QE / ml）和TAC（6.99 mg / L）和最小预计IC50（0.52 ml / mg）当功率，萃取时间，液固比，乙醇浓度和溶剂的pH分别为269.82 W，7.98 min，5.01 ml / g，73.49％和3.06％时。总体而言，可以通过优化的微波条件从茄子皮中有效提取生物活性化合物。