当前位置: X-MOL 学术Appl. Radiat. Isot. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Use of commercial pharmaceutical drug (Daktarin®) for retrospective/accidental/forensic thermoluminescence dosimetry.
Applied Radiation and Isotopes ( IF 1.6 ) Pub Date : 2020-08-01 , DOI: 10.1016/j.apradiso.2020.109364
Maria Karampiperi 1 , Nestor C Tsirliganis 1 , Nikolaos A Kazakis 1
Affiliation  

Retrospective/accidental dosimetry seeks for materials that can be used as probes for the dose assessment by means of several methods when there is no dose data available (e.g. from personal dosimeters). In the same respect, researchers also seek materials appropriate for forensic purposes, which would allow to identify the prior presence of radioactive materials at buildings, sites or even vehicles.

To this direction, several solid-state drugs, which are ubiquitous, have also been studied as probes for the dose estimation in emergency situations. However, due to their heat-sensitive character, measurements were possible only with OSL. The scope of the present work is to identify a heat-resistant drug (Daktarin) and conduct, for the first time, a detailed study of the thermoluminescence properties of it along with computerized curve deconvolution analysis which would shed light on the traps involved.

Results indicate that the glow curve of Daktarin has at least three peaks that can be used for dosimetric purposes, since they exhibit linear dose response for doses up to 20 Gy, do not exhibit any sensitization, have high lifetime and their stability with time is good, since an appreciable signal remains unaffected even 3 months post irradiation. All the above were validated conducting dose recovery tests and successfully calculating the unknown delivered dose for various periods after the irradiation of the samples. The new findings are very supportive and point towards the efficient use of commercial pharmaceuticals as probes for retrospective/accidental/forensic dosimetry using thermoluminescence.



中文翻译:

使用商业药物 (Daktarin®) 进行回顾性/意外/法医热释光剂量测定。

当没有可用的剂量数据(例如来自个人剂量计)时,回顾性/意外剂量测定法寻求可用作通过多种方法进行剂量评估的探针的材料。在同一方面,研究人员还寻求适合法医目的的材料,这将允许识别建筑物、地点甚至车辆中先前存在的放射性物质。

在这个方向上,一些无处不在的固态药物也被研究作为紧急情况下剂量估计的探针。然而,由于它们的热敏感特性,只能使用 OSL 进行测量。目前的工作范围是确定一种耐热药物 (Daktarin) 并首次对其热释光特性进行详细研究,并进行计算机曲线解卷积分析,这将阐明所涉及的陷阱。

结果表明,达克他林的辉光曲线至少有三个可用于剂量测定的峰,因为它们对高达 20 Gy 的剂量表现出线性剂量反应,不表现出任何敏化,寿命长,时间稳定性好,因为即使在照射后 3 个月,明显的信号仍然不受影响。以上所有内容均通过剂量恢复测试得到验证,并成功计算了样品辐照后不同时期的未知传递剂量。新发现非常支持,并指出可以有效地使用商业药物作为使用热释光进行回顾性/意外/法医剂量测定的探针。

更新日期:2020-08-01
down
wechat
bug