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Reducing PNS with minimal performance penalties via simple pulse sequence modifications on a high-performance compact 3T scanner
Physics in Medicine & Biology ( IF 3.3 ) Pub Date : 2020-07-30 , DOI: 10.1088/1361-6560/ab99e2
Myung-Ho In 1, 2 , Yunhong Shu 1 , Joshua D Trzasko 1 , Uten Yarach 1, 3 , Daehun Kang 1 , Erin M Gray 1 , John Huston 1 , Matt A Bernstein 1
Affiliation  

One of the major concerns associated with high-performance gradients is peripheral nerve stimulation (PNS) of the subject during MRI exams. Since the installation, more than 680 volunteer subjects (patients and controls) have been scanned on a compact 3 T MRI system with high-performance gradients, capable of 80 mT m −1 gradient amplitude and 700 T m −1 s −1 slew rate simultaneously. Despite PNS concerns associated with the high-performance gradients, due to the smaller physical dimensions of the gradient coils, minimal or no PNS sensation was reported with most pulse sequences. The exception was PNS reported by only five of 252 subjects (about 2%) scanned with a specific 3D fast spin echo pulse sequence (3DFLAIR). Rather than derating the entire system performance across all pulse sequences and all gradient lobes, we addressed reported PNS effect with a simple and specific modification to the targeted lobes of the problematic pulse sequence. in add...

中文翻译:

通过在高性能紧凑型3T扫描仪上进行简单的脉冲序列修改,以最小的性能损失降低PNS

与高性能梯度相关的主要问题之一是在MRI检查期间对象的周围神经刺激(PNS)。自安装以来,已经在紧凑的3 T MRI系统上扫描了680多名志愿者受试者(患者和对照),该系统具有高性能的梯度,能够实现80 mT m -1的梯度幅度和700 T m -1 s -1的摆率同时。尽管PNS与高性能梯度相关,但由于梯度线圈的物理尺寸较小,大多数脉冲序列的PNS感觉极小或没有。例外情况是,在252名受试者中只有五名报告了PNS(约2%),他们使用特定的3D快速自旋回波脉冲序列(3DFLAIR)进行了扫描。与其在所有脉冲序列和所有梯度波瓣上降低整个系统的性能,不如说是 我们通过对问题脉冲序列的目标波瓣进行简单而特定的修改来解决已报道的PNS效应。另外...
更新日期:2020-07-31
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