Background: The multifunctional cytokines of the tumor necrosis factor (TNF) family have been found to be involved in the promotion of inflammatory responses, and to play critical roles in the pathogenesis of inflammatory, autoimmune, and malignant diseases. The aim of the present study was to assess the associations among the TNFα −238 G > A (rs361525), TNFα −308 G > A (rs1800629), and TNFβ +252 A>G (rs909253) polymorphisms, and the breast cancer (BC) susceptibility in the Moroccan population.

中文翻译：

---

肿瘤坏死因子基因的多态性与摩洛哥人群中的乳腺癌有关。

背景：已发现肿瘤坏死因子（TNF）家族的多功能细胞因子参与炎症反应的促进，并在炎症，自身免疫和恶性疾病的发病机理中发挥关键作用。本研究的目的是评估TNFα-238 G> A（rs361525）， TNFα- 308 G> A（rs1800629）和TNFβ+252 A> G（rs909253）多态性与乳腺癌之间的关联。 BC）在摩洛哥人口中的易感性。