Grey and blue mould diseases are among the most important diseases of grapes worldwide. They are causing extensive decay in postharvest grapes. Chemical fungicides remain the primary treatment for managing these diseases. However, consumer’s interest in organic produce, restrictions on chemical use by some countries, and concerns about human and environmental safety have driven research to identify safe and effective alternatives. Among several alternative approaches, the use of biological control agents (BCAs) is getting more acceptance and has been comprehensively studied. This review summarizes the use of BCAs as a postharvest treatment to control the postharvest grey and blue mould of grapes. The review also emphasizes the economic importance of these two major postharvest diseases of grapes. In addition, other non-chemical postharvest treatments, the advantage of an integrated approach and finally problems, challenges, and future trends of the BCAs are described. Several yeasts that have a promising result to control grey and blue mould disease of grapes are thoroughly reviewed. The current market share of BCAs and their future directions on commercialization are also suggested in this review.

• Biocontrols can be a potential control method for postharvest diseases of fruits and vegetables in place of chemical fungicides.

• Antagonistic yeasts have high ability to suppress fungal growth.

• Integrated approach utilizes a combination approaches, which often results in a synergistic effect to control the diseases.

• USA and Europe are currently the largest markets for biocontrol products.

灰色和蓝色霉菌病是世界范围内最重要的葡萄病。它们导致采后葡萄的大量腐烂。化学杀真菌剂仍然是控制这些疾病的主要方法。但是，消费者对有机产品的兴趣，某些国家/地区对化学品使用的限制以及对人类和环境安全的担忧，促使人们进行研究以寻找安全有效的替代品。在几种替代方法中，生物控制剂（BCA）的使用越来越受到人们的接受，并且已经得到了广泛的研究。这篇综述总结了BCA作为采后处理来控制葡萄采后灰白霉病的方法。审查还强调了这两种主要的葡萄采后病的经济重要性。此外，描述了其他非化学的采后处理方法，综合方法的优势以及最终的BCA问题，挑战和未来趋势。彻底审查了几种在控制葡萄灰白霉病方面有希望的结果的酵母。本评论还建议了BCA的当前市场份额及其在商业化方面的未来方向。

• 生物防治可以代替水果蔬菜杀菌剂，成为水果和蔬菜收获后疾病的一种潜在防治方法。

• 拮抗酵母具有抑制真菌生长的高能力。

• 综合方法利用了组合方法，通常可以产生协同效应来控制疾病。

• 美国和欧洲目前是生物防治产品的最大市场。