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High‐yield strain of fusidic acid obtained by atmospheric and room temperature plasma mutagenesis and the transcriptional changes involved in improving its production in fungus Fusidium coccineum
Journal of Applied Microbiology ( IF 3.2 ) Pub Date : 2020-07-30 , DOI: 10.1111/jam.14797
W W Huang 1, 2 , X Y Ge 1 , Y Huang 3 , X T Chai 3 , L Zhang 2 , Y X Zhang 1 , L N Deng 2 , C Q Liu 2 , H Xu 1 , J Gao 2
Affiliation  

To obtain the high‐yield strain of fusidic acid, which is produced from fungus Fusidium coccineum and is the only fusidane‐type antibiotic that has been used clinically, and confirm the changes in the transcription levels involved in increasing its production.

中文翻译:

通过常温和室温血浆诱变获得的夫斯地酸高产菌株及其在真菌球孢镰刀菌中提高产量的转录变化

要获得由真菌镰刀菌生产的夫西地酸的高产菌株,它是临床上唯一使用的夫西丹型抗生素,并确认了增加其产量的转录水平的变化。
更新日期:2020-07-30
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