The Atlantic salmon (Salmo salar) is important to many ecosystems and local economies and has therefore become the focus of a broad range of research questions that have benefited from the availability of high-quality genomic resources. Albeit gene expression studies have been extensive for this species, the transcriptome information for Atlantic salmon whole blood has been lacking. A transcriptome of Atlantic salmon blood would be a valuable resource for future studies, especially those wishing to take non-lethal samples. Here, we report a whole blood transcriptome for Atlantic salmon constructed from twelve 8-month old salmon parr using RNA-seq. We identify transcriptomic proxies for the genotype at the major maturation timing locus vestigial-like 3 (vgll3). Differentially expressed genes between the early and late maturing genotypes showed overrepresented Gene Ontology (GO) terms with the strongest result linked to 13 ribosomal subunit genes. To assess how the whole blood gene expression profile relates to other tissues, we compare the blood transcriptome to the reference transcriptome of fourteen other tissue types using both a common PCA method and a novel method. The novel method compares transcriptomes when gene expression is visualised as a layer using thin-plate spline smoothers. Both methods found similar patterns with the blood transcriptome being quite unique compared to the transcription profiles of other tissues.

大西洋鲑鱼 ( Salmo salar ) 对许多生态系统和当地经济都很重要，因此已成为广泛研究问题的焦点，这些问题得益于高质量基因组资源的可用性。尽管对该物种进行了广泛的基因表达研究，但一直缺乏大西洋鲑鱼全血的转录组信息。大西洋鲑鱼血液的转录组将是未来研究的宝贵资源，尤其是那些希望采集非致命样本的研究。在这里，我们报告了使用 RNA-seq 从 12 只 8 个月大的鲑鱼parr 构建的大西洋鲑鱼的全血转录组。我们在主要成熟时间位点残留样 3 ( vgll3）。差异表达的基因之间的早期和晚期成熟的基因型表现出过多与链接到13个核糖体亚基基因最强的结果，基因本体论（GO）条款。为了评估全血基因表达谱与其他组织的关系，我们使用常见的 PCA 方法和一种新方法将血液转录组与 14 种其他组织类型的参考转录组进行比较。当使用薄板样条平滑器将基因表达可视化为一层时，新方法比较转录组。两种方法都发现了相似的模式，与其他组织的转录谱相比，血液转录组非常独特。