The huge amount of grape pomace generated along with wine production usually ends up as waste or with low economic value. However, due to the high content of phenolic compounds, grape pomace can be valorized through extraction. This study applied high voltage (60 kV) atmospheric cold plasma (HVACP) as a pretreatment on grape pomace for different time periods (5, 10 and 15 min) to assist in its phenolic compounds extraction, in terms of extraction yield, and the composition and antioxidant capacity of grape pomace extract. HVACP treatment was found to disrupt the epidermal cell structures of grape pomace, reduce the water contact angle of grape peels, as well as accelerate grape drying, and the effects became more significant as treatment extended. HVACP treatment also increased the yield of phenolic extracts, by 10.9–22.8%, which contained a higher concentration of anthocyanins and showed an improved antioxidant capacity (16.7–34.7%). These results demonstrate that the developed HVACP pretreatment can successfully advance the extraction of bioactive compounds by not only increasing their yield but also improving their nutritional quality. This is a promising technology for the winemaking industry to valorize grape processing byproducts for functional food and nutraceutical applications.

葡萄酒生产过程中产生的大量葡萄渣通常以废物或低经济价值而告终。但是，由于酚类化合物含量高，葡萄渣可以通过提取来增值。这项研究应用高压（60 kV）大气冷等离子体（HVACP）作为葡萄渣在不同时间段（5、10和15分钟）的预处理，以帮助其酚类化合物的提取，提取率及其组成的提取。和葡萄渣提取物的抗氧化能力。发现HVACP处理破坏了葡萄渣的表皮细胞结构，减小了葡萄皮的水接触角，并加速了葡萄干燥，并且随着处理的扩展，效果变得更加显着。HVACP处理还使酚类提取物的产量提高了10.9–22.8％，其中包含较高浓度的花色素苷，并显示出更高的抗氧化能力（16.7–34.7％）。这些结果表明，开发的HVACP预处理不仅可以提高生物活性化合物的产量，而且可以改善其营养质量，从而可以成功地促进生物活性化合物的提取。对于酿酒业来说，这是一项很有前景的技术，可用于功能性食品和营养保健品的葡萄加工副产品的增值。