Abstract

A procedure for the batch-injection amperometric determination of caffeine and theophylline using a screen-printed electrode modified with a composite based on ruthenium oxides and functionalized single-walled carbon nanotubes was developed. The effect of the parameters of the batch-injection system on the recorded signals was studied; the optimal detection conditions were selected. The analytical signal linearly depends on the concentration of compounds on the logarithmic coordinates in the range from 5 × 10^–9 to 5 × 10^–3 M. A possibility of the simultaneous batch-injection amperometric determination of caffeine and theophylline on a modified double screen-printed electrode is demonstrated. The proposed method for the determination of caffeine and theophylline was tested in the analysis of pharmaceutical preparations.

中文翻译：

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碳纳米管和氧化钌修饰的电极上的批量注射安培法测定咖啡因和茶碱

摘要

开发了一种使用丝网印刷电极分批注射安培法测定咖啡因和茶碱的方法，该丝网印刷的电极改性了基于钌氧化物和功能化单壁碳纳米管的复合材料。研究了分批进样系统参数对记录信号的影响。选择最佳检测条件。分析信号线性地取决于对数坐标上化合物的浓度，范围为5×10 ^–9到5×10 ^–3M.证明了在改进的双丝网印刷电极上同时分批注射安培法测定咖啡因和茶碱的可能性。在药物制剂的分析中测试了建议的测定咖啡因和茶碱的方法。