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Effectiveness of virtual reality games for falls, postural oscillations, pain and quality of life of individual HAM/TSP: a randomized, controlled, clinical trial.
Journal of Neurovirology ( IF 2.3 ) Pub Date : 2020-07-31 , DOI: 10.1007/s13365-020-00880-x
Naiane Araújo Patrício 1 , Diogo Guedes Vidal 2 , Elen Beatriz Pinto 3 , Katia Nunes Sá 3 , Abrahão Fontes Baptista 4
Affiliation  

People with HTLV-1 associated myelopathy or tropical spastic paraparesis (HAM/TSP) have sensorimotor losses and postural instability, resulting in frequent falls. These findings stimulate the use of exercise protocols associated with postural control. This study investigated the effectiveness of a balance training exercise protocol through a virtual game. This is a randomized crossover clinical trial performed in subjects with imbalance disorders (HAM/TSP). To evaluate postural oscillations by baropodometry (total area, anterior, posterior and lateral projection), the Footwork® system was used and by cinemetry (angle of the body, hip and ankle alignment in the lateral view), the CVMob system. In addition, the Brief Pain Inventory and the WHOQoL Bref were used to measure pain intensity and quality of life. Comparison tests of the averages (intra and inter groups) and correlations were applied considering an alpha of 5% and power of 80%. The study was approved by the Ethics Committee of the Catholic University of Salvador and registered in the Clinical Trials database (NCT02877030). The final sample consisted of 26, predominantly female subjects. An increase in the postural oscillations of the control subjects (p < 0.05), a reduction in the occurrence of falls (p = 0.039) and an improvement in the quality of life of the control-test group (p < 0.05) were observed. Virtual game training did not improve the static balance, promoting an increase in postural oscillations. Immediately after the application of the protocol, there was a reduction in fall occurrence and improvement in the quality of life.



中文翻译:

虚拟现实游戏对跌倒、姿势摆动、疼痛和个体 HAM/TSP 生活质量的有效性:一项随机、对照、临床试验。

患有 HTLV-1 相关脊髓病或热带痉挛性下肢轻瘫 (HAM/TSP) 的人有感觉运动丧失和姿势不稳定,导致频繁跌倒。这些发现刺激了与姿势控制相关的运动方案的使用。本研究通过虚拟游戏调查了平衡训练锻炼方案的有效性。这是一项在患有失衡障碍 (HAM/TSP) 的受试者中进行的随机交叉临床试验。为了通过气压测量法(总面积、前部、后部和侧向投影)评估姿势振荡,使用了 Footwork® 系统,并通过电影测量法(侧视图中的身体角度、臀部和脚踝对齐)评估了 CVMob 系统。此外,Brief Pain Inventory 和 WHOQoL Bref 用于测量疼痛强度和生活质量。考虑 5% 的 alpha 和 80% 的功效,应用了平均值(组内和组间)和相关性的比较测试。该研究获得了萨尔瓦多天主教大学伦理委员会的批准,并在临床试验数据库(NCT02877030)中注册。最终样本包括 26 名,主要是女性受试者。控制对象的姿势摆动增加(p  < 0.05),观察到跌倒发生率降低 ( p  = 0.039),对照组的生活质量提高 (p < 0.05)。虚拟游戏训练并没有改善静态平衡,促进姿势摆动的增加。应用该方案后,跌倒发生率立即降低,生活质量得到改善。

更新日期:2020-07-31
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