Frontostriatal disconnectivity plays a crucial role in the pathophysiology of major depressive disorder. However, whether the baseline functional connectivity of the frontostriatal network could predict the treatment outcome of low-dose ketamine infusion remains unknown.

中文翻译：

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额叶皮层与纹状体的功能性连接障碍可预测难治性抑郁症的氯胺酮输注反应。

额纹状体断开在重度抑郁症的病理生理学中起着至关重要的作用。然而，额纹状体网络的基线功能连接是否可以预测低剂量氯胺酮输注的治疗结果仍然未知。