Although the pro-inflammatory cytokine, interleukin (IL)6, has been generally regarded as “depressogenic”, recent research has started to question this assumption, in light of the fact that this cytokine can also have anti-inflammatory properties. This bimodal action seems to be dependent on its concentration levels, and on the concomitant presence of other pro-inflammatory cytokines.

中文翻译：

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白细胞介素 (IL6) 的体外促炎和抗炎特性：与重度抑郁症和人类海马神经发生的相关性。


尽管促炎细胞因子白细胞介素 (IL)6 通常被认为具有“抑制作用”，但最近的研究已开始质疑这一假设，因为该细胞因子也具有抗炎特性。这种双峰作用似乎取决于其浓度水平以及其他促炎细胞因子的同时存在。