Abstract

Background

The objective of this paper was to evaluate the potential individual and combined effects of acute exercise coupled with bilateral interhemispheric activation on episodic memory function. Six experiments were conducted.

Methods

Experiment 1 was a within-subject, counterbalanced experiment. Participants completed four visits, including 1) exercise and saccadic eye movements, 2) exercise only, 3) saccadic eye movements only, and 4) no exercise and no saccadic eye movements (control). A word-list memory assessment was employed, including a long-term (20-min delay) memory evaluation. In Experiment 2, we evaluated the effects of saccadic eye movements on prefrontal cortex oxygenation, a proxy for neuronal activity. Similarly, in our third experiment, we evaluated the effects of acute exercise on prefrontal cortex oxygenation. Thus, experiments 2 and 3 were employed to provide mechanistic insights from the results shown in experiment 1. Experiment 4 replicated Experiment 1, but instead of increasing prefrontal cortex activation via saccadic eye movements, we used a fist clenching protocol. Experiment 5 evaluated the effects of fist clenching on prefrontal cortex oxygenation.

Results

Collectively, these 5 experimental studies showed that acute exercise (Experiment 1), saccadic eye movements (Experiment 1), and fist clenching (Experiment 4) enhanced memory function, and that acute exercise (Experiment 3), saccadic eye movements (Experiment 2) and fist clenching (Experiment 5) all increased prefrontal cortex oxygenation. Experiment 6 demonstrated that prefrontal cortex oxygenation was positively associated with episodic memory function.

Conclusion

These six experiments suggest that several behaviors, such as acute exercise, saccadic eye movements and fist clenching may improve memory function and may, potentially, do so via increases in prefrontal cortex oxygenation.

中文翻译：

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运动行为诱导的前额叶皮层激活和情景记忆功能

摘要

背景

本文的目的是评估急性运动结合双侧大脑半球激活对情景记忆功能的潜在个体和综合影响。进行了六次实验。

方法

实验 1 是一个受试者内的平衡实验。参与者完成了四次访问，包括 1) 运动和眼跳，2) 仅运动，3) 仅眼跳，和 4) 不运动且没有眼跳（控制）。采用单词列表记忆评估，包括长期（20 分钟延迟）记忆评估。在实验 2 中，我们评估了眼跳对前额叶皮层氧合（神经元活动的代表）的影响。同样，在我们的第三个实验中，我们评估了急性运动对前额叶皮层氧合的影响。因此，实验 2 和 3 被用来从实验 1 中显示的结果中提供机械见解。实验 4 复制了实验 1，但不是通过增加前额叶皮层激活眼跳，我们使用了握拳的协议。实验 5 评估了握拳对前额叶皮层氧合的影响。

结果

总的来说，这 5 项实验研究表明，急性运动（实验 1）、扫视运动（实验 1）和握拳（实验 4）增强了记忆功能，而急性运动（实验 3）、扫视运动（实验 2）和握紧拳头（实验 5）都增加了前额叶皮层的氧合。实验 6 表明，前额叶皮层氧合与情景记忆功能呈正相关。

结论

这六个实验表明，一些行为，如剧烈运动、眼球运动和握拳可能会改善记忆功能，并且可能通过增加前额叶皮层氧合来实现。