In intensive farming systems, fish are held at high densities, which may increase stress, leading to susceptibility to diseases that result in economic losses. Therefore, effective feeding practices incorporating health‐promoting compounds such as proteins, hydrolysates and bioactive peptides that can stimulate the defence mechanisms of fish and achieve better growth are some of the priorities for sustainable aquaculture development. Globally, the fish processing industries generate and discard a large volume of waste every year, estimated at up to 60% of the harvested biomass. This waste can be converted to value‐added products such as fish protein hydrolysate (FPH) with the addition of various proteolytic enzymes. FPH from fish processing waste including skin, heads, muscle, viscera, liver and bones is a good source of protein, amino acids, peptides and antioxidants and has been found to possess desirable functional and bioactive peptides. A moderate inclusion of FPH in aquafeeds has the potential to improve growth, feed utilization, immune functions and disease resistance of fish. Production of FPH, targeted to more precise molecular weight ranges, has superior functionalities that are in high demand. With interest in FPH as an aquafeed supplement, this review aimed to summarize the source, production processes and functional properties of FPH and the reported impact of FPH in aquafeed supplement on fish growth, survival, feed utilization, immune response and disease resistance. Possible limitations of using FPH and future research potential as an opportunity for the use of processing fish waste are also discussed.

中文翻译：

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有鳍水产养殖中酶促鱼蛋白水解物的研究进展

在集约化养殖系统中，鱼类被养在高密度的地方，这可能增加压力，导致对疾病的敏感性，导致经济损失。因此，有效的饲喂方法结合了促进健康的化合物，例如蛋白质，水解产物和生物活性肽，可以刺激鱼类的防御机制并实现更好的生长，这是可持续水产养殖发展的优先事项。在全球范围内，鱼品加工业每年产生并丢弃大量废物，估计占所收获生物量的60％。可以通过添加多种蛋白水解酶将这些废物转化为增值产品，例如鱼蛋白水解物（FPH）。来自鱼类加工废物（包括皮肤，头部，肌肉，内脏，肝脏和骨骼）的FPH是蛋白质，氨基酸，肽和抗氧化剂，并发现它们具有理想的功能和生物活性肽。在水产饲料中适当添加FPH可能会改善鱼类的生长，饲料利用率，免疫功能和抗病能力。以更精确的分子量范围为目标的FPH的生产具有对功能的高度需求，这是非常需要的。由于对FPH作为水产饲料补充剂的兴趣，本综述旨在总结FPH的来源，生产过程和功能特性，以及FPH在水产饲料补充剂中对鱼类生长，存活，饲料利用，免疫反应和抗病性的影响。还讨论了使用FPH的可能局限性和未来的研究潜力，将其作为加工鱼粪的机会。