The microwaves‐assisted extraction (MAE) for concentration of cherry phytochemicals has seen explored. Polyphenols from cherries, Prunus avium (L.) L., were extracted using a microwave oven at 2,450 MHz, 453 W for a period of 60 s (T60), and was compared versus an unprocessed MAE extract (T0). The extracts were analyzed for total polyphenols, total anthocyanins, and antioxidant capacity. THP‐1 cells were stimulated with monosodium urate (MSU) crystals at 150 µg/ml for 24 hr. Cherry extracts were added to cultures concurrently with MSU or 3 hr before MSU addition as pretreatments. Reactive oxygen species (ROS), IL‐1β levels, and MSU crystal phagocytosis were evaluated. T60 extract showed a higher concentration of polyphenols, anthocyanins, and antioxidant activity than T0 extract. ROS were inhibited using the 1:800 and 1:1,600 (v:v) dilutions from both extracts, even used as pretreatments. IL‐1β levels and MSU crystal phagocytosis were reduced. Cherry is a source of polyphenolic compounds with antioxidant and anti‐inflammatory activity.

中文翻译：

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樱桃提取物可减轻THP-1细胞中尿酸一钠晶体触发的炎症和氧化应激。

人们已经探索了微波辅助萃取（MAE）浓缩樱桃植物化学物质的方法。樱桃，李属樱桃中的多酚（L.）L。，使用微波炉在2,450 MHz，453 W下提取60 s（T60），并与未处理的MAE提取物（T0）进行比较。分析提取物中的总多酚，总花青素和抗氧化能力。用尿酸一钠（MSU）晶体以150 µg / ml刺激THP-1细胞24小时。将樱桃提取物与MSU同时或在添加MSU之前3小时添加到培养物中作为预处理。评估了活性氧（ROS），IL-1β水平和MSU晶体吞噬作用。与T0提取物相比，T60提取物显示出更高的多酚，花色苷和抗氧化活性。使用两种提取物中的1：800和1：1,600（v：v）稀释液都可以抑制ROS，甚至可以用作预处理。IL-1β水平和MSU晶体吞噬作用降低。