The reactions of the triosmium carbonyl cluster Os₃(CO)₁₀(NCCH₃)₂ (1) with a number of protected amino acids, tri- and pentapeptides were examined. The results show that reaction with the side chains follow the order: -SH > -COOH > -CONH₂, and there is a slight preference for the longer side chain of glutamic acid over aspartic acid. The trends observed are retained under physiological conditions and in the peptides.

中文翻译：

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理解细胞毒性羰基三os簇Os ₃（CO）₁₀（NCCH ₃）_{2的作用方式}：其与氨基酸和寡肽的反应性

羰基三tri簇Os ₃（CO）₁₀（NCCH ₃）₂（1）与许多受保护的氨基酸三肽和五肽的反应得到了检验。结果表明，与侧链的反应遵循以下顺序：-SH> -COOH> -CONH ₂，并且谷氨酸的侧链长于天门冬氨酸略有偏爱。在生理条件下和肽中保留了观察到的趋势。