An effective development platform for custom lab-on-a-chip and lab-on-a-foil solutions has been regarded as a missing element for wider adoption of microfluidic technologies in everyday life. We have used a direct laser structuring device combined with CAD-CAM software and have developed an efficient, fast, and precise procedure for rapid prototyping of widely accessible contemporary materials utilized for flexible microfluidics. Utilization of an ultra-short pulsed laser has enabled us to predict and control the laser ablation process on thin low-temperature co-fired ceramics and Kapton foil. We have demonstrated an agreement between the theoretic predictions and experimental data on ablation rates, paving the way to a fully predictive manufacturing process. Our procedure enables an independent control of microfluidic channel shape, depth, and lateral dimensions down to 10 µ m, while maintaining an exceptional process quality achieved by a parametrically optimized laser o...

中文翻译：

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使用直接激光快速成型解决方案精确制造柔性微流体电路

用于定制芯片实验室和箔实验室解决方案的有效开发平台已被视为在日常生活中广泛采用微流体技术的要素。我们已使用直接激光结构化设备与CAD-CAM软件相结合，并且已经开发出了一种高效，快速，精确的程序，可以快速原型化用于柔性微流体的广泛使用的当代材料。超短脉冲激光的使用使我们能够预测和控制薄的低温共烧陶瓷和Kapton箔上的激光烧蚀过程。我们已经证明了理论上的预测与消融速率的实验数据之间的一致性，为完全预测性的制造过程铺平了道路。我们的程序可独立控制微流体通道的形状，深度，