Aluminium nitrate and other aluminium-containing compounds have been demonstrated to cause several health challenges. Psidium guajava L) is a well known cultivated tree with hepatoprotective nature and radical scavenging ability. Twenty-five (25) female Wistar rats with average weight of 195 g were grouped into five groups (n = 5), with their weights measured and recorded weekly throughout the period of 21 days of the research. Control (group A), 32.5 mg/kg AL only (group B), 30 mg/kg AL + 250 mg/kg PGLE (group C), 20 mg/kg AL + 500 mg/kg PGLE (group D) and 10 mg/kg AL + 750 mg/kg PGLE (group E). Histological examination of the liver was done using Hematoxylin and Eosin stain. Various degenerative changes were observed in the liver architecture following aluminum nitrate administration when compared with the control group. Significant regenerative changes similar to control were observed following administration of high dose of Psidium guajava. The results obtained in this study revealed that aqueous extract of Psidium guajava leaves possess good hepato-protective properties.

中文翻译：

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番石榴叶水提取物对硝酸铝诱导的雌性Wistar大鼠肝损伤的改善作用

硝酸铝和其他含铝化合物已被证明会对健康构成挑战。番石榴（Psidium guajava L）是一种众所周知的栽培树，具有保肝性和清除自由基的能力。将二十五（25）只平均体重为195 g的雌性Wistar大鼠分为五组（n = 5），在研究的21天中每周进行一次体重测量和记录。对照组（A组），仅32.5 mg / kg AL（B组），30 mg / kg AL + 250 mg / kg PGLE（C组），20 mg / kg AL + 500 mg / kg PGLE（D组）和10毫克/千克AL + 750毫克/千克PGLE（E组）。使用苏木精和曙红染色对肝脏进行组织学检查。与对照组相比，硝酸铝给药后在肝脏结构中观察到各种退行性变化。施用高剂量番石榴后，观察到与对照相似的显着再生变化。这项研究获得的结果表明，番石榴叶的水提物具有良好的肝保护特性。